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Managing Side Effects and Maximizing Weight Loss Success Nausea, the most common semaglutide side effect, typically peaks 35 days post-injection and resolves by day 7 as your body adjusts to the medication

Taking a GLP-1 injection slightly early is generally not harmful, but doses given too close together may increase the risk of side effects such as nausea, vomiting, or abdominal discomfort

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