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Practice Pearls: Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral drugs for type 2 diabetes that inhibit the breakdown of glucagon-like peptide-1 (GLP-1) and increase the release of insulin in response to a meal

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Due to its extended half-life and structural modifications, GLP-1 is commonly selected for studies requiring prolonged receptor engagement and sustained signaling observation

Data now demonstrates that patients receiving a placebo alongside behavioral therapy lost only 2.8% of their starting weight after 24 weeks, while those who added phentermine experienced weight loss of 5.9%

When the right key is inserted, a series of activities is unlocked. In this case that key is GLP-1 and the unlocked activities are the release of insulin and the curbing of the production of glucagon

Direct-to-patient healthcare company Ro is using the biggest stage in advertising to pivot the conversation around GLP-1s