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Increasing evidence has demonstrated that GLP-1 analogues can cross the blood-brain barrier, protect dopaminergic neurons in the substantia nigra, and rescue motor activity and cognitive functions in PD animal models (5961)

These cases had a subtle onset and were accompanied by nonspecific symptoms such as malaise, myalgias, abdominal pain, respiratory distress, or increased somnolence

Healthy individuals typically have Akkermansia making up 1 to 4 percent of their total gut bacteria

Additionally, resistance training provides the necessary stimulus to maintain or even build muscle, even when overall weight is decreasing (Phillips & Van Loon, 2011)

Appetite 21 , 95104 (1993)

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