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Early research has not found an increased risk of major developmental issues during early pregnancy from GLP-1 exposure

Contraindications GLP-1 is not recommended if you have a family history of medullary thyroid cancer or a history of pancreatitis
Abstract Current pharmacological treatments for bipolar disorder are inadequate and based on serendipitously discovered drugs often with limited efficacy, burdensome side-effects, and unclear mechanisms of action
doi: 10.1186/s13195-020-00646-x 9 ElahiFMAlladiSBlackSEClaassenJDeCarliCHughesTMet al

New targets: SMAD3 adaptor SPTBN1 Liver-specific knockout of SPTBN1 in mice protects against obesity, providing a potential therapeutic avenue for metabolic disorders (Rao et al

This dual-action mechanism is what sets tirzepatide apart from other options
