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The pathological factors mentioned above, as well as hyperandrogenism (40), together play important roles in the development of low-grade inflammation in PCOS, and these factors also interact with one other, thus creating a vicious circle (41, 42)

The function of metformin in upregulating GLP-1R level and PKA phosphorylation in endothelial cells may contribute to the synergistic protective effect of this combination therapy, which provides new insights on the interaction between metformin and GLP-1 agents (Fig

GLP-1R has been detected in healthy thyroid cells other than C cells, as well as in some papillary thyroid cancers (75)

were responsible for and A.S

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Temporally ordered associations between type 2 diabetes and brain disordersa Danish register-based cohort study
