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Brock C, Hansen CS, Karmisholt J, Moller HJ, Juhl A, Farmer AD, et al

In an early clinical trial, exenatide combined with sulphonylureas resulted in an elevated incidence of mild-to-moderate hypoglycemia (27)

Triple-Hormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial New England Journal of Medicine (2023) PubMed In 338 adults with obesity, retatrutide 12 mg produced 24.2% body weight loss at 48 weeks

No increased risk of heart failure hospitalization of major cardiovascular events observed with liraglutide in patients with or without a history of heart failure results from the LEADER trial

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While the GOLO diet is relatively healthy, customers are largely paying for the supplements