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Together, these medications act on the brains hunger and reward centers, making it easier to manage portions, resist cravings, and stay consistent with lifestyle changes.

Semaglutide and tirzepatide are among 20 new additions to the WHO's list of essential medicines.

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Seventy-two week outcomes from the SURMOUNT-5 clinical trial have shown that tirzepatide (Zepbound) met the primary endpoint and all five key secondary endpoints, demonstrating superiority, compared to semaglutide (Wegovy) across the trial.The detailed results were presented at the 32nd European Congress on Obesity (ECO) and simultaneously published in The New England Journal of Medicine.SURMOUNT-5 was a 72-week, multi-centre, randomised, open-label, Phase 3b trial evaluating the efficacy and