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Published online April 8, 2026

For patients also taking insulin or sulfonylureas, it's important to note that hypoglycaemia can cause symptoms including sweating and shakiness, which might be confused with feeling cold

The highest approved dose of oral semaglutide (14 mg/day) is currently indicated only for treating T2DM as an adjunct to diet and exercise

Drinking too little fluid can also contribute to constipation, headaches, and fatigue

It does not tighten skin

Naylor, Louise
