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JAMA Surgery
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They are rapidly and efficiently absorbed after oral administration, exhibiting high bioavailability ranging from 67% to 100%, except for linagliptin, which has a bioavailability of 30% as a result of its first pass metabolism in the intestine and hepatocyte, and limited membrane permeability [73, 74] (Table 1)
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Habener and his team had to switch from a rat model to a cold-blooded animal model for their genetic research
