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Never inject through clothing or into irritated, scarred, bruised, or tattooed skin, as these areas may impair absorption or increase infection risk

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By stimulating insulin release and suppressing glucagon secretion (a hormone released by the liver that increases glucose in the bloodstream), GLP-1s contribute to reduced blood sugar levels

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This review aims to evaluate the current evidence on GLP-1s as it relates to bone metabolism, wound healing, and surgical outcomes, with the goal of informing clinical decision-making and guiding future research in orthopedic surgical care