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Clin Pharmacokinet 2019;58:11931203 [DOI] [PMC free article] [PubMed] [Google Scholar] 47

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Among patients on weekly GLP-1/GIP medications, the proportion of patients without clinically significant RGV was significantly higher in those who held the medication for more than 3 days (38 patients [92.7%]) compared with 3 days or less (5 patients [62.5%]) ( P = .047)

After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo

After GLP-1 injection, heart rate returned to near-baseline levels within 30 min ( Figure 4A )

Effects of liraglutide on no-reflow in patients with acute ST-segment elevation myocardial infarction