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However, the health benefits are often even more significant for older individuals because they are at higher baseline risk for obesity-related diseases

[DOI] [PubMed] [Google Scholar] 111.Zelniker T.A., Wiviott S.D., Raz I., Im K., Goodrich E.L., Furtado R.H.M

Bottom line (short) Tirzepatide is a novel dual GIP/GLP-1 receptor agonist that produces substantially greater average weight loss (in SURMOUNT-1 up to ~21% with 15 mg at 72 weeks) than placebo and larger weight and A1c reductions than some comparator GLP-1 therapies in trials

Rapid calorie reduction

If fatigue persists despite these measures, your physician may consider adjusting your medication regimen

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