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And I also thought that was interesting what you said about infection and these post-infectious things that can happen that people with hypermobility are at increased risk

This is partly due to tirzepatide's mechanism of action as a double agonist, permitting it to assert a more significant decrease in hyperglycemia as compared to glucagon-like peptide (GLP-1) agonists on their own [8]

Barreto-Vianna ARC, Aguila MB, Mandarim-de-Lacerda CA

The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort, affecting up to 40% of patients initially

Therefore, while GLP-1RAs may represent a promising therapeutic option for managing psoriasis, further high-quality studies are needed to distinguish whether the therapeutic effects of GLP-1RAs originate from the direct regulation of immune cells or improvements in comorbidities such as obesity or diabetes