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Among these lesions, stroke accounts for the highest proportion [1]

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: Systematic review and network meta-analysis of randomised controlled trials

In a clinical trial in pediatric patients aged 12 years with normal baseline heart rate, more patients treated with Wegovy injection compared to placebo had maximum changes in heart rate of 20 bpm or more (54% vs 39%)

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Uncontrolled hypertension despite treatment with two or more antihypertensive medications "Uncontrolled" generally means a systolic blood pressure consistently above 140 or a diastolic above 90 despite ongoing treatment with at least two antihypertensive medications from different drug classes (such as an ACE inhibitor or ARB, a calcium channel blocker, a thiazide diuretic, or a beta-blocker)

Sample size, patient characteristics (age, gender, BMI, diabetes duration)