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1 February 2023

For instance, insulin and sulfonylurea drugs when used in combination with these medicines can lead to dangerously low blood sugar levels

As part of the incretin hormones, GLP-1 has three known mechanisms of action: activating glucose-dependent insulin secretions, thereby reducing plasma glucose, suppressing glucagon secretion, and delaying gastric emptying [3]
Farxiga CKD Dosing : Standard dose: 10mg once daily Used when eGFR 25-75 mL/min/1.73m Continue even as eGFR declines to 25 mL/min/1.73m Monitor for volume depletion Jardiance CKD Dosing : Standard dose: 10mg once daily Used when eGFR 20 mL/min/1.73m May continue until dialysis initiation Regular kidney function monitoring is essential Both medications slow kidney function decline and may be continued longer than traditional diabetes medications as CKD progresses

It reduces markers of muscle protein breakdown

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