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GLP-1 receptor agonists (GLP-1 RAs) with exenatide b.i.d
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Semaglutide was removed in February 2025
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Pfizers dose-optimization studies of once-daily formulations of danuglipron ( NCT06567327 and NCT06568731 ) met key pharmacokinetic objectives and confirmed a formulation and dose with the potential to deliver a competitive efficacy and tolerability profile in Phase 3 testing, based on earlier studies of twice-daily danuglipron
