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These are promising results, but the studys authors note that more research is needed, and clinicians must also consider potential adverse effects, evaluate the cost-effectiveness of these medications for each patient, and closely monitor for any improvement or worsening of eating disorders and related side effects. That hesitation is shared by the National Eating Disorder Association (NEDA), who published an opinion paper on GLP-1s and eating disorders in 2024, stating: While there is some evidence that GLP-1s can decrease the number of binge eating episodes for those with BED, little is known about the long term physical and psychological impact on those with eating disorders. How GLP-1s could also fuel eating disorders The same mechanisms that make these medications helpful for some could make them harmful for others

At approved weight-loss doses, caloric intake typically decreases in a consistent and measurable way

Does the type of semaglutide formulation (brand name vs compounded) affect drug test results

Hence, inhibition of MMP-9 secretion by GLP-1 and its products results in thickening of the fibrous cap and increased collagen content of the plaque, improving its stability

The major clinical trials (SURPASS for diabetes, SURMOUNT for weight management) did not identify anxiety as a common adverse event

For all my complaining about the price, these are drugs that we should want to give to lots of people, but its been really hard to see how we can afford them. Rind said he doesnt expect prices to drop further anytime soon not until other drugs in development are approved, which likely wont happen for a few more years