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Nonetheless, the interpretation of current data is limited by detection and prescription biases in observational studies as well as insufficient follow-up and number of events in randomized trials

10.7554/eLife.50208 7 FengY.SuL.ZhongX.GuohongW.XiaoH.LiY.et al (2016)

Temporal trends in discontinuation reasons were described across the study period

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GLP-1 RA-Related Facial Aging The rapid and significant weight loss induced by GLP-1 RAs often leads to a noticeable reduction in facial fat pad volume, along with a decline in skin collagen, elastin, and essential nutrients

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