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Reduction in lesion count

GLP-1 acts through its receptor, GLP-1R, which is a class B G-protein-coupled receptor (GPCR)

b , i , l , o , Venn-diagram with differentially regulated proteins (DRPs) over vehicle in pancreas ( b ), eWAT ( i ), liver ( l ) and skeletal muscle ( o )

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Proc Natl Acad Sci USA 2009;106:340813

By targeting both GIP + GLP-1 pathways, it helps patient achieve more effective and sustainable weight loss when combined with proper medical guidance and lifestyle changes