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Semaglutide plus trevogrumab (myostatin inhibitor) preserves muscle mass in the setting of #weightloss over 26 weeks Regeneron #Weight 11.3% with combination vs 10.4% sema alone 4.2 lbs muscle with combination vs 7.9 lbs muscle with sema alone 18.9 lbs fat with combination vs 15.3 lbs fat with sema alone

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This graph diagrams utilization, unit cost, and cost as a percent of overall medical cost trend: note that by the middle of 2023, GLP-1 drug costs for Group health plan members comprised 13.6% of a major pharmacy benefit management (PBM) company, shown in the third bar

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