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India faces the double burden of obesity and non-communicable diseases, being the diabetes capital

Setting realistic expectationsexplaining that maximum benefits may take 3 months to manifest and that gastrointestinal side effects typically improve with timeenhances treatment persistence and patient satisfaction with this therapeutic approach

GLP-1RAs such as semaglutide are known to cross the bloodbrain barrier, suggesting that their pain-relieving effects could be mediated through brain structures such as the hypothalamus and brainstem, areas that regulate nociception [102]

The findings were striking: for every 5 kg increase in weight or every inch added to waist circumference, the likelihood of RA onset climbs

Preliminary evidence suggests that a 12-Week treatment with tirzepatide plus low-energy ketogenic therapy is more effective than its combination with a low-calorie diet in preserving fat-free mass, muscle strength, and resting metabolic rate in patients with obesity
HF is closely related to cardiometabolic diseases such as diabetes, obesity and chronic kidney disease, and strategies that address most or all these intertwined conditions are desirable