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65 Multiple RCTs show that semaglutide and tirzepatide improve symptoms of HFpEF more dramatically than any prior therapy

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The ongoing EVOKE trials evaluating semaglutide in Alzheimer's disease represent a potentially transformative pipeline catalyst that, if successful, could open an entirely new application segment of substantial scale by the early 2030s

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However, a fixed day of the week is far more important than a fixed hour, as it strengthens habit formation and simplifies side-effect tracking