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We conducted secondary analyses of four other prediabetes definitions: HbA 1c 3947 mmol/mol (5.76.4%) only

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To assess heterogeneity, Chi-square and I 2 statistics were utilized, with significant heterogeneity defined as a p -value below 0.1 and an I 2 exceeding 50%

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Future research endeavors could consider employing additional approaches, such as prospective clinical trials or evidence-based cohort studies, to overcome some of the limitations associated with FAERS data

It stimulates collagen and elastin synthesis through cellular signaling rather than requiring increased protein substrate availability
