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The muscle loss with GLP-1 is real and the risks of sarcorpenia are real as we go into the future, so it is important to have guidance in this at Prevention Clinics

As previously mentioned, because DPP-4 inhibitors can increase the risk of hypoglycemia when added to insulin or a sulfonylurea, a dose decrease of sulfonylurea and/or insulin should be considered prior to initiation of a DPP-4 inhibitor

Also referred to as oral semaglutide drops or semaglutide sublingual, companies market these products as a convenient, needle-free way to achieve the same results as injectable GLP-1 medications

If you're talking about blood sugar and fullness signals and all that, it makes sense that you're doing it with meals, although I could see why people might think doing it between meals could have its own positive effect of potentially reducing your hunger signals, for example

Cardiometabolic Risk Beyond BMI Body mass index has long served as a convenient marker for identifying obesity-related health risks