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Patients with a history of thyroid tumors or certain types of thyroid disease may need to explore alternative treatment options
The Grading of Recommendations Assessment, Development and Evaluation framework (GRADE) system was applied to assess the certainty of evidence for each outcome

Metformin declines the number of disease-associated bacteria such as Intestinibacter spp., Bacteroides fragilis , and Clostridioides difficile (de la Cuesta-Zuluaga et al., 2017

Weight-related concerns often come with questions about safety and oversight

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