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In the positive control group, 200 g of Semaglutide in 100 L of PBS was injected subcutaneously into the animals on day 0, 7, 14, and 21

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J Clin Endocrinol Metab 1993;76:79-84.ArticlePubMed 45
GLP-1 agonists demonstrate potential beyond metabolic benefits, targeting inflammatory mechanisms underlying ulcerative colitis through pathways observed in preclinical research. For overweight patients with ulcerative colitis, these medications offer dual benefits: reducing inflammation while facilitating weight loss , which itself may decrease disease activity