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Given the apparent signal of occasional acute pancreatitis in patients treated with GLP-1based therapy, how do we reassure ourselves that asymptomatic chronic pancreatitis is not also induced in some patients

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Gene set enrichment analysis (GSEA) unmasked increased expression of genes involved in the positive regulation of ROS metabolic process and regulation of apoptotic process in isolated IgWAT after MN-MP/aUCP1 + US treatment, which proved that US-augmented genome editing treatment effectively enhanced ROS production and induced apoptosis of adipocytes (Fig