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Bossart M, Wagner M, Elvert R, Evers A, Hbschle T, Kloeckener T, et al

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Clin Kidney J

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This superior efficacy helped it achieve global sales of ~US$16.4bn in 2024 (Mounjaro ~US$11.5bn and Zepbound ~US$4.9bn), rivalling semaglutide and completely overshadowing the sales of historical GLP-1s, such as exenatide, liraglutide and dulaglutide [FIGURE TWO]

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Various impurities may be present in peptides, including missing or incorrectly inserted amino acids, incorrectly folded peptides, impurities due to oxidation or hydrolysis, isomers, or leftover reagents [1]

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Prescribing information: TANZEUM (albiglutide) for injection, for subcutaneous use

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Jama, 2022

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