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recruited 281 participants with T2DM living with overweight or obesity who were randomized to receive once-weekly injections of placebo, 1.5 mg of GLP-1RA dulaglutide, or tri-agonist retatrutide maintenance doses of 0.5 mg, 4 mg (starting dose 2 mg), 4 mg (no escalation), 8 mg (starting dose 2 mg), 8 mg (starting dose 4 mg), or 12 mg (starting dose 2 mg)

Pfizer said in a press release that an asymptomatic volunteer in the companys studies experienced potential drug-induced liver injury, which resolved after stopping the medication

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But once I started taking a GLP-1, I was down for the count till lunchtime. And that was after just one or two drinks

The 60S acidic ribosomal protein P0 (Rplp0) (Mm00725448) was used as the endogenous control gene