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Third, most trials have short follow-up periods, and long-term efficacy, safety data, and relapse rates in the context of smoking cessation remain lacking

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Thus, GLP-1 RAs were first introduced in 2005 when the FDA approved exenatide for glycemic control in T2DM

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very low certainty of evidence) relative to SGLT2 inhibitor or GLP-1 RA monotherapy

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