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By pairing a rapid "research flywheel" with large-scale genomic data, 23andMe Research Institute scientists identified GLP1R and GIPR variants associated with some of the variability in individual response to GLP-1 drugs, helping bridge the gap between patient experiences and precision medicine.

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The incretin hormone glucagon-like peptide 1 (GLP-1) has been implicated in the gutrenal axis and incretin-based therapies might reduce the burden of diabetic kidney disease

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A large global retrospective cohort study (n=331,863 matched patients

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