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Caputo, A
[13] The current NICE obesity guideline sets out a structured approach involving lifestyle interventions as a first-line measure, licensed pharmacotherapy where clinically appropriate, and bariatric surgery for eligible individuals with severe obesity
But the mechanism goes deeper than appetite suppression

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GLP-1 agonists are not a substitute for insulin
A summary of all the CV events occurring during these trials are presented in Additional file 1: Table S1
