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Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): A 56-week, double-blind, phase 3a, randomised trial

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Nevertheless, with the extension of the follow-up, these therapeutic efficacies weakened

The latest International Diabetes Federation (IDF) report indicates a 10.5% prevalence of T2DM in adults in 2021, projected to reach 12.2% by 2045 (Sun et al., 2022
