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It terms of where to inject Semaglutide, it must be injected subcutaneously (into the fat layer)

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2,3 Stretching of the PIP volar plate can occur during disease progression, leading to hyperextension of the PIP and subsequent flexion of the DIP joints

The first drugs in the GLP-1 class were liraglutide (under the brand names Victoza and Saxenda), which were approved for diabetes and weight management, respectively, in 2010 and 2015

Mitchell JL, Lyons HS, Walker JK et al (2023) The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial
