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Finally, in the ELIXA trial, the GLP-1 receptor agonist lixisenatide was shown to reduce UACR by 39% in people with macroalbuminuria at baseline, despite very modest effects on hemoglobin A 1c (0.3%) and body weight (0.7 kg) (13)

doi:10.1097/fbp.0000000000000818 16.Garvey WT, Blher M, Osorto Contreras CK, et al

(20) In separate study, Hansen et al

Manufacturers must strike a delicate balance between access, value perception, and sustaining profitability in the context of reimbursement constraints