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These barriers can disrupt weight-loss treatment and lead to medication switching
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In addition to their insulinotropic effects, GIP and GLP-1 play critical roles in various biological processes in different tissues and organs that express their receptors, including the pancreas, adipose tissue, bone, and the brain

New research shows that GLP-1 receptors exist throughout the body, particularly in areas outside the pancreas and including the central nervous system, cardiovascular system, and immune cells [4,5]

The guidance has also been updated to include the 24-hour fluid diet recommendation