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A proteomic study begins to identify the direct and indirect effects of GLP-1 treatment on metabolic dysfunction-associated steatohepatitis (MASH), and reveals insights into treatment-induced changes in liver histology.

Summary-data-based MR (SMR) and IVW were used to calculate the effect estimates

Then, docking candidates were validated and further performed signal pathway via Caco-2, C2C12, and AR42J cells

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