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These arent isolated stories the pattern has caught the attention of neuroscientists, addiction specialists, and the broader medical community

P.ShtengelG.et al

The absence of leg cramps from official labeling does not definitively rule out a connection, as post-marketing experience sometimes reveals adverse effects not detected in pre-approval trials due to sample size limitations, duration of follow-up, or patient population differences

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More specifically, the 200mg group saw a 2.4% reduction, while the 400mg and 800mg groups experienced reductions of 1.9% and 1.7%, respectively

Understanding this can help set realistic expectations about the benefits of hormone therapy