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We do not know what the future will look like, but for now, it is possible that people will be discontinued on their medication, whether semaglutide or tirzepatide, while the manufacturers ramp up supply to try to meet this unprecedented demand

It is available only as a generic formulation

While gastrointestinal side effects dominate the clinical trial headlines, dry mouth quietly affects a meaningful number of people taking GLP-1 medications

For those working with compounded semaglutide , the flexibility to choose precise intermediate doses (0.75 mg, 1.25 mg, 1.5 mg) makes the titration smoother

Sundaram S, Yan L

Placebo: Participants in both trials typically lost less than 3% of their body weight