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In SUSTAIN FORTE, subgroup analyses by baseline use of metformin with or without a sulphonylurea were only available for changes from baseline in HbA1c and body weight at week 40

Backed by nearly six of real-world clinical data, Calibrate members achieve sustained outcomes that exceed results from medication alone

Long-term use may lead to vitamin B12 deficiency, requiring regular monitoring

Ignoring progressive symptoms can lead to severe clinical complications, such as acute pancreatitis, extreme dehydration, or a bowel obstruction

These effects can make it easier to consume fewer calories and eat more nutritious foods

GLP-1 medications work by increasing insulin secretion, decreasing glucagon secretion, delaying gastric emptying, and reducing appetite, which collectively lead to weight loss and improved metabolic health
