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The class of drugs, which includes Novo Nordisks Ozempic and Wegovy, are associated with the risk of gastrointestinal adverse events when used for weight loss, finds a study published Thursday in JAMA.

Agents in this group include antioxidants (vitamin E), tumor necrosis factor pathway regulators (emricasan, pentoxifylline, ZSP1601), and immune modulators (cenicriviroc, belapectin)

Pharmaceutical company Novo Nordisk, maker of blockbuster weight loss drug Wegovy, says its CEO is stepping down.

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We hope to provide inspiration and ideas for future studies in the mechanism and targets of HO-1 through this review.