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GLP-1 medication helps calm appetite and reduce the physical stress of dieting, but it works best when paired with daily choices that protect muscle

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35% relative risk reduction), and death from any cause (5.7% and 8.3%, respectively

When your stomach emptying is delayed by medication, it can be harder to rehydrate quickly

For instance, in January 2025, the FDA approved semaglutide (Ozempic) as a medication to reduce the risk of kidney failure, kidney disease progression, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease (CKD)

In practice, physical dependence at prescribed doses is rare