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Diepenbroek C, Quinn D, Stephens R, Zollinger B, Anderson S, Pan A, et al

Due to massive and persistent cultural and patient resistance and restrictive regulations, opioid-based OUD treatments like methadone and buprenorphine are used by a small fraction of people who could benefit from them

The fasting trial showed 15% less rebound eating four hours after the last dose, confirming 4-6 hour duration
doi:10.1016/j.cmet.2018.03.001 Lau J, Bloch P, Schffer L, et al

The risk was 0.2% in people taking GLP-1s and 0.1% in those who didnt

doi: 10.1016/j.metabol.2024.156100
