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Major US medical organizations including ACOG, The Menopause Society, and NASEM have concluded that compounded bioidentical hormone therapy claims of superior safety or effectiveness over FDA-approved hormone therapy are not substantiated by evidence from well-designed clinical studies, and that FDA-approved hormone therapy products are generally recommended over compounded alternatives when an FDA-approved formulation appropriate to the patient is available

Ongoing long-term randomized trials will be essential to confirm these observational data and establish the durability of liver-related benefits

Diabetes: An Old Disease A New Insight 111 Keating GM (2010) Vildagliptin: a review of its use in type 2 diabetes mellitus
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Lastly, consider consulting a registered dietitian for individualized support
