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People prescribed the new generation of weight loss drugs may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss, say experts at UCL and the University of Cambridge.

The phrase usually refers to compounded or off-label dosing schedules that sit below 5 mg per week, sometimes at 2.5 mg or even 1 mg, marketed as a way to capture the appetite suppression and modest weight loss without the gastrointestinal side effects that hit hardest at higher doses

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