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Furthermore, validation has been achieved with small molecules such as GSK137647A, which activates the Free Fatty Acid Receptor 4 (FFAR4, also known as GPR120), and with Sinigrin, an agonist of the Bitter Taste Receptor 38 (TAS2R38)

Conflict of interest All authors are employed full time by GNC Holdings, LLC

Fintini D, Grugni G, Brufani C, Bocchini S, Cappa M, Crino A

Bridge (July 1, 2026-December 31, 2027): Medicare Part D enrollees can access GLP-1 medications for weight loss or weight maintenance for $50 per fill

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Ethics declarations Competing interests J.R., S.W., J.N., P.T., C.P., L.L., Y.H., A.I.R., J.A.S