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doi:10.1038/s41584-025-01302-0

These impacts will be especially pronounced for middle-aged and elderly adults, who will experience HOTs as a stunningly effective anti-aging and rejuvenation therapy

Thus, a systematic review of the efficacy of GLP-1RAs in terms of their effect on the underlying pathology of AD and improvement of cognitive functions, which included 6 articles that met the criteria (4 randomized control studies and 2 protocol studies) [53], indicates that GLP-1RA therapy in AD did not alter -amyloid and tau protein biomarkers and did not improve cognitive abilities, but demonstrated potential metabolic and neuroprotective benefits

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Front Endocrinol (Lausanne) 11:617400 McClean PL, Irwin N, Cassidy RS, Holst JJ, Gault VA, Flatt PR (2007) GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

When you sleep less, you have more time to eat