glp 1 agonist alcohol GLP-1 receptor agonists are promising but unproven treatments for and substance use disorders Does GLP-1 Stop Alcohol Cravings?

DPP-4 inhibitors are one of the few oral agents that are useful in patients with significant renal impairment

Liu, Recent Advances in Non-Peptidomimetic Dipeptidyl Peptidase 4 Inhibitors: Medicinal Chemistry and Preclinical Aspects, Curr

Several mechanisms may be involved in this potential association, some of which include sudden weight loss and hyperactivity of the hypothalamic-pituitary-adrenal axis

Inker LA, Eneanya ND, Coresh J, et al

Endogenous GLP-1 has short-lived effects, but pharmaceutical GLP-1 RAs are engineered to have far longer half-lives and therefore sustained physiological impact

Published August 2, 2023