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Risk of hypoglycemia Theres a risk of low blood sugar (hypoglycemia) when using GLP-1 agonists

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The reason gut flora convert berberine into DHB is because, unlike berberine, DHB can pass through intestinal tissue, which enables it to reach the bloodstream

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Stay at the current dose until GI symptoms have resolved for at least two full weeks

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When A1C is $9% (75 mmol/mol), consider initiating dual combination therapy (Fig

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N Engl J Med 2016;375:31122.ArticlePubMedPMC 46

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