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Description
Methods Cell Biol 107:6792
References Wegovy (semaglutide 2.4 mg) Prescribing Information U.S
Lost 20-30 pounds versus 50-80 pounds (less biological drive toward regain) Genuine lifestyle transformation during treatment
When switched to placebo there was invariably weight regain, implying that the loss of inhibition of hyperphagia drove this process
Realworld studies demonstrate high discontinuation rates of GLP1RAs by up to 75% within the first year of use, predominantly driven by side effects 20-22
Two popular options are Pep , a specialized GLP-1 shot and health tracker, and Lose It
